What is Vitamin B6?

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that plays a vital role in numerous physiological processes. It is involved in over 100 enzyme reactions, mainly related to protein metabolism. 

This vitamin is essential for brain health, immune function, and the production of hemoglobin, a component of red blood cells.

How Does Vitamin B6 Benefit Hair Health?

1. Protein Metabolism: Vitamin B6 aids in the metabolism of proteins, which are essential for hair structure. Hair is primarily made of keratin, a protein that requires adequate levels of Vitamin B6 for its synthesis.

2. Hormonal Balance: Vitamin B6 helps regulate hormones, including androgens. Excessive androgens can lead to hair thinning and loss, particularly in conditions like androgenic alopecia. By modulating hormone levels, Vitamin B6 may help prevent hair loss.

3. Scalp Health: The vitamin supports the production of hemoglobin, which ensures that the scalp receives sufficient oxygen and nutrients. A healthy scalp environment is crucial for hair growth.

4. Reduction of Dandruff: Pyridoxine can help in managing dandruff, a common scalp issue that can contribute to hair loss if left untreated. It helps to reduce sebum production, which in turn minimizes dandruff formation.

Sources of Vitamin B6

Vitamin B6 is found in a variety of foods, making it relatively easy to include in your diet:

• Animal Sources: Poultry, fish (like salmon and tuna), and organ meats (such as liver) are rich sources.
• Plant Sources: Potatoes, bananas, chickpeas, and fortified cereals contain significant amounts of B6.
• Supplements: If you’re not getting enough Vitamin B6 from your diet, supplements are available. However, it’s important to consult with a healthcare provider before starting any supplementation.

Daily Recommended Intake

• Adults (19-50 years): 1.3 mg/day
• Men (51 years and older): 1.7 mg/day
• Women (51 years and older): 1.5 mg/day
• Pregnant Women: 1.9 mg/day
• Breastfeeding Women: 2.0 mg/day

These values may vary based on individual health needs, and certain conditions may require higher intake.

Signs of Vitamin B6 Deficiency

A deficiency in Vitamin B6 can lead to various symptoms, some of which may affect hair health:

• Dermatitis: Scaly patches on the scalp.
• Hair Thinning: Due to disrupted protein metabolism and hormone imbalance.
• Irritability and Depression: Can indirectly affect hair health by causing stress, a known trigger for hair loss.

Risks of Excessive Vitamin B6 Intake

While Vitamin B6 is crucial, excessive intake (above 100 mg per day) can lead to toxicity. Symptoms include:

• Nerve Damage: Leading to numbness and tingling in the extremities.
• Skin Lesions: Which could negatively impact scalp health.

Conclusion

Vitamin B6 is a critical nutrient for maintaining hair health due to its role in protein metabolism, hormone regulation, and scalp health. A balanced diet rich in B6-containing foods is usually sufficient to support hair growth and prevent hair-related issues. 

However, if you're considering supplementation, it’s essential to consult with a healthcare provider to avoid potential side effects from excessive intake.

* For safer and improved results, HR23+ Hair Restoration Supplement has recently lowered its daily amount of Vitamin B6 from 100mg to 10mg.  

HR23+® is a top non-prescription solution for hair loss, formulated to prevent further hair thinning and promote healthy hair growth in men and women experiencing early signs of baldness and hair thinning.

HR23+® has become Europe’s leading non-medical hair supplement, with 9 out of 10 users reporting significant improvements in their hair within 3 to 6 months.

How Does HR23+® Work?

HR23+® addresses hair loss by leveraging a blend of potent antioxidants designed to shield cells, including those in the scalp, from oxidative stress caused by free radicals. The supplement is infused with extracts that are high in bioactive elements—such as flavonoids and terpenoids—recognised for their antioxidant and anti-inflammatory qualities.

These antioxidants and anti-inflammatory properties support hair health by enhancing circulation, reducing oxidative damage, decreasing scalp inflammation, and reactivating dormant hair follicles. Collectively, these ingredients foster essential biological processes like cell signalling, cell growth, and the formation of cell membranes, creating a more favourable environment for hair vitality.

HR23+® also contains anti-androgenic ingredients intended to limit the conversion of testosterone into Dihydrotestosterone (DHT), a hormone linked to hair thinning in androgenetic alopecia (pattern baldness) and other hair loss conditions. Lowering DHT levels can help reduce hair loss and support natural regrowth, particularly beneficial for those with early signs of hair thinning.

A core ingredient, epigallocatechin gallate (EGCG), a powerful antioxidant and anti-inflammatory polyphenol, works to defend hair follicles from damage and reduce inflammation in the scalp, supporting healthier hair growth. Additionally, pumpkin seed extract, paired with saw palmetto, helps inhibit DHT production to curb hair thinning. Other critical components like horsetail extract, nettle leaf extract, and saw palmetto enhance blood flow to hair follicles and protect them from damage, supplying the nutrients needed for optimal growth.

HR23+® also includes silica, an essential element for collagen production, which helps strengthen hair strands. Vitamins like biotin (B7) and folic acid (folate) contribute to healthy hair growth, while minerals such as zinc and copper aid in bolstering hair strength and promoting growth.

These nutrients support numerous cellular functions and act as enzyme cofactors for DNA and RNA synthesis, which are crucial for the formation of new hair cells. HR23+® is a specially crafted supplement that tackles hair loss at its roots, providing a top-tier, non-medical option for hair health.

Effectiveness of HR23+®

Since its release in 2015, HR23+® has garnered a high success rate among non-medical hair supplements. Nearly 90% of users report noticeable improvements in hair density, growth rate, or reduced hair loss within the first 3 to 12 weeks of use. The supplement is particularly effective for individuals in the initial stages of hair loss, although results may vary for those with advanced hair thinning.

HR23+® Results in Numbers

• 92% of male and female users repurchase the product
• 85% of male users report visible improvements
• 91% of female users notice a difference
• 65% of users observe visible results within 3 months

HR23+® is a non-medication, vegan-friendly hair supplement that avoids major side effects. Made in the United Kingdom, it is recommended by trichologists and featured in hair clinics across the UK as an effective tool for hair loss management. It is currently undergoing clinical trials to establish certification as a recognized non-medical hair loss treatment for both men and women.

With growing evidence from users and professionals, HR23+® is often considered one of the most effective supplements for early-stage hair loss and thinning.

Expected Outcomes with HR23+®

• Significant reduction in hair shedding
• Quicker, stronger hair growth
• Hair regrowth in some cases

Usage Guidelines

Take four capsules daily with water, either split into two doses (morning and evening) or all at once. If stomach sensitivity occurs, take with food. Store the bottle in a cool, dry, and shaded area, and keep the silica gel packet inside the bottle until finished.

 

Saw palmetto has been extensively studied for its role in preventing hair loss, particularly in androgenetic alopecia (AGA), the most prevalent type of hair loss. 

This plant-derived extract is thought to function as a 5-alpha-reductase inhibitor, similar to medications like finasteride. By reducing the conversion of testosterone into dihydrotestosterone (DHT)—a hormone associated with hair follicle miniaturization—saw palmetto may help slow or mitigate hair loss.

Enhanced Efficacy Through Combination Therapies

Although saw palmetto shows promise in reducing hair loss, research indicates it is more effective when combined with complementary ingredients. Several synergistic combinations have been explored to boost its efficacy, particularly for managing AGA.

1. Saw Palmetto + Biotin

Biotin, a B-vitamin essential for keratin production—the primary protein in hair—is often included in hair-loss treatments. While biotin deficiency is rare, supplementation can strengthen hair and support growth.

• Supporting Evidence: A 2015 study involving a nutraceutical blend of saw palmetto, biotin, and other nutrients showed marked improvements in hair density and quality within 12 weeks.

2. Saw Palmetto + Pumpkin Seed

Pumpkin seed oil contains phytosterols and compounds that inhibit DHT production while offering anti-inflammatory benefits for scalp health.

• Supporting Evidence: A 2014 randomized trial found that pumpkin seed oil alone increased hair growth by 40% in men with AGA over 24 weeks. Combined with saw palmetto, these effects may be amplified.

3. Saw Palmetto + Zinc

Zinc contributes to hair follicle recovery and inhibits DHT synthesis. Deficiency in zinc is associated with hair thinning, and supplementation can improve hair density and strength when paired with saw palmetto.

4. Saw Palmetto + Green Tea Extract (EGCG)

Green tea extract, rich in epigallocatechin gallate (EGCG), has demonstrated DHT-inhibiting properties and the ability to stimulate hair growth. This combination leverages complementary mechanisms: reducing DHT levels and promoting active follicle growth during the anagen phase.

5. Saw Palmetto + Nettle Leaf

Nettle root acts as a natural DHT inhibitor and is rich in silica, which strengthens hair strands. Anecdotal evidence suggests that pairing nettle leaf with saw palmetto can enhance DHT-blocking effects, though more scientific research is warranted.

HR23+ strategically combines saw palmetto with these complementary ingredients, increasing the potential for slowing hair loss and promoting regrowth.

 

This case study highlights the experience of Participant 4, a 35-year-old male with advanced male pattern baldness, classified as stage 4+ on the Norwood Hamilton scale. 

Over a six-month period, the participant followed a dual-approach treatment combining HR23+ hair health supplement and daily applications of minoxidil 5% solution. 

The trial aimed to evaluate the effectiveness of this regimen in promoting hair growth, improving density, and reducing hair loss. Below, we detail the participant's progress and outcomes throughout the study.

Participant 4 Overview

• Gender: Male
• Age: 35
• Hair Loss Stage: Norwood Hamilton 4+
• Trial Duration: 6 months

Participant 4 presented with male pattern baldness, classified at stage 4+ on the Norwood Hamilton scale, characterized by overall scalp thinning. During the six-month trial, the participant followed a regimen of four daily HR23+ hair health supplement capsules combined with the daily application of a 5% minoxidil solution.

Results After Six Months

Following six months of consistent use, Participant 4 reported noticeable improvements in hair health. Key outcomes included:

• Increased density along the frontal hairline.
• Thicker hair growth across the hairline and the rest of the scalp.
• A significant overall increase in hair density.